Protein Chemistry Laboratory

Research in the Protein Chemistry Laboratory is aimed at an understanding of protein interactions with small molecules, other proteins and nanoparticles. The increasing use of peptides as therapeutics has prompted us to look into the various aspects of these interactions to try and understand the impact on disease related processes. A brief outline of the different projects: Protein aggregation studies: Aggregation studies currently underway involve several proteins as well as the amyloid peptide fragment Ab25-35which represents the biologically active and toxic domain of the full length Aβ peptide, responsible for Alzheimer’s disease. Inhibition of amyloid fibrillation of the Aβ25-35 peptide…