Bridging the divide

A novel Science Communication Conclave at IIT Kharagpur tries to bridge the gap between the scientific community and the media to pave the way for better news dissemination

Veteran science journalist Ms. T.V. Padma during her talk

February 28 was the day C.V. Raman went to the media to disclose to the world his discovery of the ‘Raman effect’. What better way to celebrate National Science Day, as this day is known, than re-energize the bond between the scientific community and its messengers and interlocutors – the media? That is precisely what IIT Kharagpur’s two-day Science Communication Conclave 2020 has done. This unique initiative of the Institute brought together top science journalists and communicators throughout India, researchers, faculty and students to deliberate on how best to disseminate news from the world of science and technology.

Prof. Sriman Bhattacharyya

In his address to the audience, Prof. Sriman Kumar Bhattacharyya, Deputy Director, IIT Kharagpur, pointed out, “National Science Day is a reminder of the importance of science dissemination and it should be done by any means possible.”

Was this task of dissemination of news related to science and technology anyway being jeopardized by scientists’ reservations about opening up to the media? Were journalists jeopardizing the intent and purpose of communication in their hurry to ‘break news’? Is scientific jargon serving as a barrier to the correct representation of scientific developments? Is science news becoming less popular? Could there be ways to spur its popularization?

Prof. Baidurya Bhattacharya, Dean, International Relations

The congregation of mediapersons, scientists, as well as students took a hard look at the issues at hand. Prof. Baidurya Bhattacharya, Dean, International Relations, convenor of the event, set the tone by opening the conclave with a presentation on the development of cloning technology that at once highlighted the follies and expected rigour of reportage on a scientific development. “There is an enormous need to disseminate factually correct information and at the same time to live up to the demands of the media industry,” said Prof. Bhattacharya.

Panel discussion on ‘Role of alternative media in science dissemination’

For some years now, science news have taken a backseat in traditional media. Supplements dedicated to science have been dropped and science news have shrunk often to half a page being devoted to it. Senior journalists, such as Ms. T.V. Padma and Mr. Dinesh Sharma, highlighted the problems facing science journalism today – organizationational constraints of the media houses who were dependent on advertisements, the preference for ‘breaking news’, low priority for science news vis a vis political news and news from the world of entertainment, the lack of mentoring of science journalists, the lack of infrastructural support or of networking bodies.

Dr. Meher Wan, , Editor of Indian Journal of Engineering and Materials Science

They also drew attention to what they called ‘communication bottlenecks’ with the scientific community that were adding to the troubles. Often, scientists’ unwillingness to publicly communicate on research and the lack of an institutional policy on communication complicated matters.

Despite the drawback, senior journalists such as Mr. Pathik Guha (Anandabazar), Mr. Amal Sarkar (Ei Samay), Ms. Padma, Mr. Sharma, Mr. B.R. Srikanth, and a younger crop, such as Mr. Mohamad Shafi Shamsi, Mr. Indrajit Kundu, Mr. Sujoy Dhar, or Mr. Shwetank Dubey, were making all out efforts to encourage public interest in science through innovative ways of story-telling or through the use of more visual elements such as infographics.

In fact, alternative media appear to be making a major advance in this respect by opening up ways for better and more impactful science communication. “We live in the times of ‘convergence media’,” remarked Mr Sujoy Dhar, correspondent for Reuters in Kolkata and a writer for Inter Press Service (IPS), pointing to the enormous advantages of online news dissemination.

Ms. Sahana Ghosh

Ms Satarupa Sen Bhattacharya, National Editor at Citizen Matters, an online civic media platform that researches and reports on critical urban issues, pointed out, “Online has a lot of space and can also experiment with different formats. It is a foregone conclusion that videos, podcasts and photoessays have a lasting impact and can catch a readers’ attention further.”

Ms Sahana Ghosh, staff writer with Mongabay, an international science news website, said, “With sound graphics, infographics, and other visuals, a story can be told in a wonderful manner. There is also scope for collaborations and cross-disciplinary work. The advantage for scientists lies in the fact that we can create high impact small packets of information and these are easy to digest.”

Ms. Ipsa Jain

The conclave also showcased the works of two science communicators with a difference – Ms Ipsa Jain, currently a Postdoctoral Fellow at the Institute of Stem Cell Biology and Regenerative Medicine, Bengaluru, who uses art and aesthetics as a vehicle for storytelling, and Lipsa Panda, currently working as a visual research communicator for the Lancet and FT commission, who also holds a PhD in Respiratory Immunology from CSIR- IGIB, Delhi. “Science cannot be breaking news but it has to be disseminated. A quick check and you will see that newspapers have 20 million readers, but Facebook has 2.9 billion, and YouTube 1.9 billion…. These are the platforms through which you can bring awareness about what kind of research you are trying to do, and this awareness can create interest so the audience will eventually demand to read science news,” argued Lipsa at a panel discussion on the ‘Role of alternative media in taking science to a wider audience’.

The poster exhibitions of the work of Ms. Jain and Ms. Panda at the conclave, which drew a lot of attention, clarified their point even better.

How could the scientific community help the media in its efforts for wider news dissemination? The discussions at the conclave seemed to suggest a few ways.

For one, greater cooperation between scientifists and mediapersons. “Remember, we are not adversaries. We need each other to take the news of science to the people,” said Prof. Pallab Dasgupta, Professor at the Department of Computer Science and Engineering, who was also panellist at the discussion titlted “Lab to media – bridging the language gap”.

A greater interaction with mediapersons, in fact, had helped both Prof. Abhijit Mukherjee, renowned hydro-geologist and Associate Professor, Geology and Geophysics, and Prof. Bhargab Maitra, a noted expert in urban planning and development, and transportation and Head of the Ranbir Chitra Gupta School of Infrastructure Design and Management and Professor at the Department of Civil Engineering at IIT Kharagpur, to make an impact at the level of policy-making. Both of them pointed this out during their talk at the conclave.

Another way that emerged from the discussions was training scientists and researchers on public communication. Several among IIT Kharagpur’s faculty acknowledged the need for it to ensure correct reportage of scientific developments. Some like Prof. Suman Chakraborty, Professor at the Department of Mechanical Engineering and Dean of the Office of Sponsored and Industrial Research Consultancy at IIT Kharagpur, had already started the initiative by asking his students to put down their research work in the simplest possible language. “The more effective the communication, the more effective the way the journalist can disseminate the news. In fact, this kind of training is part and parcel of advanced research for students around the world,” said Prof. Chakraborty.

Prof. Swagata Dasgupta

A host of IIT faculty talked about new and emerging areas of research. Prof. Swagata Dasgupta on protein chemistry, Prof. Sudeshna Sarkar on Artifical Intelligence, Prof. Saibal Gupta on ‘analogous studies’ of planetary topography, Prof. Chacko Jacob on nanomaterials and new materials, Prof. Brajesh Dubey on waste management, Prof. Sangeeta Bhattacharya on public health matters and Prof. Dilip Swain on food security. Many of them cautioned the media against hype.

Prof. Partha Pratim Chakrabarti

As Prof. Sunando Dasgupta, Professor at the Department of Chemical Engineering and Head of the Advanced Technology Development Centre, IIT Kharagpur, pointed out, “Science is a process of inquiry. You cannot expect breaking news to happen on a daily basis… For example, there can be no breaking news in cancer cure. It is an ongoing work and the steps that we take are at best incremental. But yes, scientists need to explain what they are doing. However, they are not trained to communicate what they are doing.”

Prof. Partha Pratim Chakrabarti, former Director of IIT Kharagpur, left a lasting impression with his concluding talk on Vigyan Katha Sagar, his proposed mission to take science to school children through Next-gen stories that embed principles of modern science and technology and enable critical thinking. Prof. Chakrabarti wrote, “The talk was inspired by the timeless masterpiece – Kathasaritsagar and its immense potential for a revisit. I illustrated the untapped power of simple age-old stories like Thirsty Crow in modern light and gave a sample of some of my own initial attempts at story-telling on problems solving and algorithm design meant for school students. Request others to share their ideas and possible stories.”

 

The Cop from Kgp

Ashish Tiwari, IPS, Senior Superintendent of Police, Ayodhya, Uttar Pradesh and IIT Kharagpur alumnus has been conferred the Director General of Police (DGP), UttarPradesh (UP), Commendation Disc (Gold), 2020 and gfiles Awards 2019 for good governance and Smart e-Police innovation.

Ashish graduated from IIT Kharagpur in 2007 with B.Tech. and M.Tech. Dual Degree in Computer Science and Engineering. He pursued the career of an investment banker with Lehman Brothers and Nomura before joining Indian Revenue Service as Assistant Commissioner of Income Tax and then opting for Indian Police Service (2012 batch). 

Ashish was in-charge of maintenance of law and order during the historical Ayodhya verdict last year. His technological brainchild, the Smart e-Police is now hailed as a significant innovative platform which is helping UP police major leaps forward in today’s digital world.

Smart e-Police is a solution to solve serious internal and external problems of the police force and citizens through SMART (Simple and Sensitive, Moral and Modern, Accountable, Reliable and Responsive, Trained and Technical) policing. It includes challenges in terrorism, corruption, traffic jams, missing children, corruption, crimes, women and senior citizens safety, verification, slow police reforms, quality service delivery etc. by amalgamation of old processes with new technologies under ‘One Nation, One App’ concept of the police department. The system has been successfully deployed in identifying and busting fake news by raising social awareness among the citizens.

Ashish has also constituted green groups for rural women to counter domestic violence, drug and alcohol abuse, gambling etc.

We congratulate this young Kgpian who serves as an inspiration for the talented youth across the country and motivate them to serve the nation.

Advancing Industrial Workforce

IIT Kharagpur’s Advanced Manufacturing Technology Centre Creating Nexgen Workforce for India’s Manufacturing Industry

The Centre of Excellence in Advanced Manufacturing Technology at IIT Kharagpur organized a five-day training programme on Computer Numerical Control (CNC) for industry professionals and technicians. The Centre, which was set up with support from the Department of Heavy Industry (Ministry of HI&PE), Govt. of India and a consortium of six industrial houses and a startup, has a mandate of creating awareness regarding advanced technologies, reskilling and upskilling of the Indian MSMEs and youth. CNC, being the core of any manufacturing equipment, is an essential pack of knowledge, one must have.

The training program targeted a diverse group of participants including students undergoing diploma courses and from ITI colleges, laboratory technicians, graduate degree students, teachers, and industry personnel. The training programme equipped the participants with knowledge of programming and detailed machine operations essential for CNC jobs in the manufacturing industry. 

A unique trend was the presence of female participants which is indicative of opportunities of women’s employment on the machining shop floor as programmers and operators.

“In today’s era of Industry 4.0, the manufacturing platform is being transformed and integrated with digitization. But if you look at the connection between our capital goods sector and the MSMEs this transition is not without disruptions. Our Centre of Excellence will help the industries including MSMEs to upskill their work-force through training on the automation concepts like CNC, Robotics, etc.” remarked Prof. Surjya K Pal, Professor in-Charge of the Centre.

The teachers and students participating in the training programme expressed practicality of such training on a shopfloor-like platform with industry scale CNC machines. Witnessing the overwhelming response, the Centre is now geared up to offer a similar training programme in the next 2-3 months. 

Various large, medium and small enterprises have shown interest to join the consortium of this CoE. Four Tata companies are associated with this consortium where our faculty colleagues are closely working with them on Industry 4.0, automation and Additive Manufacturing areas. The Centre has created an Innovation Lab where anybody can access the state of the art facility by paying nominal charges.

“We are also planning to float training opportunities on Machine Centre by using the state-of-the-art 5-axis Machining Centre, Industrial Robotics, and Robotic Welding by using the upcoming state-of-the-art robotic welding facility at this Centre of Excellence,” Pal added.

This Centre of Excellence in Advanced Manufacturing Technology also offers a unique platform for collaborative research in manufacturing keeping harmony with the ‘Make-in-India’ initiative of the Govt. of India. The Centre initiates innovative and top-quality research focused towards the industries on Specialty materials, Design and automation, Additive manufacturing, and Industry 4.0 (Industrial Internet of Things). The Centre boosts innovative interventions in the advanced manufacturing domain by enabling an ecosystem among Institutes of higher repute, top industries, and also the MSMEs & start-ups. The Centre also energizes the MSMEs through training, short-term courses on the adoption of modern concepts in manufacturing.

Reaching Out to Rural Community

IIT Kharagpur Reaches out to Village Youth at the Agri Food Expo 2020 for Skill Development and Entrepreneurship in Rural Technologies

with contributions from Guru Sanjeev Kumar

The Dept. of Agriculture & Food Engineering organized the Agri Food Expo 2020 during February 14-16, 2020, under the Unnat Bharat Abhiyan programme of the Government of India. A Workshop on Technologies for Skill Development and Entrepreneurship was conducted wherein 300 participants from West Bengal and neighbouring states were trained. The workshop was primarily targeted towards unemployed rural youth who at least have a college degree and a zeal to undertake livelihood projects. The participants included representatives from 34 colleges, and district officers from West Bengal, Jharkhand and Odisha.

The areas of training involved Operation, Maintenance and Repair of Farm Machinery & Farm Implements, Green House and Drip Irrigation Technology, Soil Testing, Vermi-composting Technology & Organic Farming, Rice milling & Rice puffing Technology, Food Processing and Preservation Technology, Effective Storage techniques for Fruits and Vegetables, Solar Technology, Extrusion Technology, Bio-fertilizers and Bio-pesticide Production Technology from Organic Wastes, Water Quality Measurement, Bee Keeping (Apiculture), Mushroom Farming, Betel Leaf Technology and various other Rural Technologies.

The participants visited the research laboratories at the Institute and Experimental Farms, Rural Energy Park and Science & Technology Entrepreneurship Park for demonstrations machineries, processes and food processing technologies developed by IIT Kharagpur and various industries. Lectures and discussions were also held in these areas.

A key concern of the participants regarding challenges by the rural community in adapting to new technologies was a point of discussion.

Prof. P B S Bhadoria, coordinator of Unnat Bharat Abhiyan at IIT Kharagpur said, “in recent years introduction of technologies has led to economic empowerment and improved livelihood of rural community. This has been achieved by means of outreach initiatives through various colleges.” 

The inaugural ceremony was attended by prof. V K Tewari, Director, IIT Kharagpur, Prof. B N Singh, Registrar, IIT Kharagpur, Prof. Vivek Kumar from IIT Delhi, Prof. Aditya Bandyopadhyay from IIT Kharagpur and many others.

Leading the Emerging Economies Ranking

IIT Kharagpur Ranked 32nd Globally and 2nd in India in Times Higher Education Emerging Economies Ranking 2020, Jumps 24 Places

Graphic: Suman Sutradhar

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IIT Kharagpur has been ranked 32nd in the Times Higher Education Emerging Economies Ranking 2020 making it the top IIT and the second-ranked institution in India. The Institute which was ranked 55th last year has jumped 24 places within 12 months with improvement in the areas of both Teaching and Research. However, the real game-changer has been the Institute’s Industry Income.

Overall India has 56 institutions represented in the ranking with 18 of them featuring in the top 100 and IISc being the top-ranked institution from India. Mainland China is the most-represented nation with 81 institutions with India occupying the second position and Brazil at third with 46 institutions. More than 530 universities feature in this year’s table – almost 100 more than last year – hailing from 47 countries, up from 43.

The ranking is done based on full-time equivalent students at the institute, student-to-staff ratio, international students, female-to-male ratio. The Emerging Economies University Rankings use the 13 carefully calibrated performance indicators grouped into five areas: Teaching (the learning environment); Research (volume, income and reputation); Citations (research influence); International outlook (staff, students and research); and Industry income (knowledge transfer).

Talking about this stellar improvement, Prof. V K Tewari, Director, IIT Kharagpur said, “IIT Kharagpur in the recent past has taken measures to maintain a globally competitive faculty-student ratio while ensuring best-in-class quality. The faculty and surging number of researchers have also delivered high output and impact in research. These two factors serve as obvious criteria to attract industrial collaborations and grants coming in.”

He also remarked on strategies being undertaken by IIT Kharagpur beyond such rankings.

“We will have to aim towards achievements similar to the global universities of repute which are also considered among the world’s top ten. To achieve those we are actively engaging with all our stakeholders including alumni, faculty, students, industrial and foreign collaborators, and most importantly the ministries of Govt. of India,” he added.

Apart from faculty, student and income data collected from the institutions and research data from Scopus, the ranking methodology also involves extensive surveys with academicians and researchers.

“This is just the beginning and IIT Kharagpur has taken several initiatives to strengthen the academic and research as well as industrial outreach, providing quality education and diverse academic disciplines. The strength being inter-disciplinary schools and centres collaborating with the departments on cutting edge research topics” said Prof. G P Raja Sekhar, Dean, Planning & Coordination.

The Emerging Economies University Rankings includes only institutions in countries classified by the Financial Times Stock Exchange as “advanced emerging”, “secondary emerging” or “frontier”.

“Institutions in the Emerging Economies University Rankings have unique characteristics, and we reflect these in our methodology by adjusting the performance indicators in our gold standard World University Rankings to place them,” states a communique from the ranking body.

The report further reveals that there is a little correlation between rankings performance and higher education investment or university access. However, many of the top performers in terms of the overall score are from Europe’s emerging economies and may have benefited due to regional neighbours with stronger traditions of higher education and research.

Ellie Bothwell, rankings editor and international reporter at Times Higher Education said, “countries’ overall performance in the Times Higher Education Emerging Economies University Rankings is linked more closely to geographic factors than to their level of economic development.”

The evolving grammar of healthcare

The Clinical Biomarkers Discovery Laboratory at IIT Kharagpur is actively involved in using the newly emerged field of metabolomics, which is capable of providing biological end-point markers of the cellular processes that occur as a result of disease. The lab focuses on the use of metabolomics for comprehensive identification of disease biomarkers and understanding of the pathogenic mechanism underlying complex human diseases. Prof. Koel Chaudhury, who heads the lab, talks to the KGP Chronicle about how she has used the metabolomics approach to investigate women’s health, the progress her team has made and the future challenges.

Could you please give a brief summary of your research in the medical/life sciences domain?

The approach to illness and disease management has changed considerably with the evolution of medicine. In the past, medicine was strictly practiced according to the symptoms presented by the patient and was essentially based on the individual expertise of the physician, and thus was known as intuition medicine. Presently, medicine is based on the evidence produced by scientific research which also include the clinical trials, and is termed as evidence-based medicine. Most of the medical treatments today are designed for the average patient using the “one-size-fits-all” approach. Unfortunately, this type of treatment is seen to be very successful for some patients but not for others. In future, medicine is to be practiced according to algorithms that will take into consideration the patient’s characteristics, e.g. their genome, epigenetics, microbiomes, proteomes, metabolomes, environments and lifestyle to make diagnostic and therapeutic strategies precisely tailored to individual patients. It is envisioned that this will lead to the emergence of an effective P4 (predictive, preventive, personalized and participatory) healthcare system.

Our team uses the multi-omics approach including quantitative proteomics, NMR and mass spectrometry-based metabolomics to identify robust biomarkers in serum/urine/tissues/exhaled breath condensates/bronchoalveolar fluid which can assist in early disease prediction, identify disease sub-categories and predict individual disease risk. We also use ‘omics’-driven studies to enhance our understanding of the disease pathogenesis and monitor the therapeutic effect of drugs so that personalized therapeutic strategies targeting the underlying disease etiology can be developed.

What are the challenges that the research will help address?

Some of the clinical research questions our team is presently addressing using the ‘omics’ approach are listed below:

  1. What is the underlying cause of unexplained recurrent miscarriage?
  2. Can a set of biomarkers be developed for early prediction of spontaneous miscarriage (during first trimester of pregnancy, i.e. <12 weeks of gestation)?
  3. Can Stage I endometriosis (usually exists without signs and symptoms) be diagnosed early?
  4. What is the pharmacometabolomic effect of the drug dydrogesterone (a synthetic form of progesterone) in women with recurrent miscarriage?
  5. Is Asthma-COPD Overlap (ACO) a new disease entity?
  6. Can serum biomarkers replace the invasive right heart catheterization diagnostic procedure in patients with pulmonary hypertension?
  7. Is differential diagnosis of the two granulomatous restrictive lung diseases, chronic hypersensitivity pneumonitis (HP) and advanced-stage sarcoidosis possible?
  8. What is the effect of long-term doxycycline in improving COPD disease conditions?

In what stage of development is this research?

  • Potential markers have been identified in the exploratory patient cohort of various diseases; validation of these promising markers is ongoing in a fresh cohort of patients
  • Long term doxycycline as a possible therapeutic option for COPD is being explored
  • Robust serum biomarkers have been identified in early stage endometriosis; fabrication of a minimally invasive multiplexed point-of-care diagnostic device for detection of these markers is underway

 What is the future of this research?

Our research is translational and interdisciplinary in nature. We have active collaboration with clinicians and faculty members of various departments within the Institute. The aim of our team is to carry out ‘omics’-driven translational health research which will provide the ideal platform to diagnose diseases early in a non/minimally invasive and cost-effective manner.

How will the upcoming Dr B.C. Roy Institute of Medical Science and Research hospital help this work?

  • Large patient cohort is needed to generate error free data for biomarker discovery studies. The 400 bed hospital will provide the ideal set-up for such high-throughput data generation.
  • Integration of metabolomic data with metabolic imaging (PET-CT) and molecular imaging will be possible, which will provide a more holistic view to the perturbations caused by the disease
  • Discovering new drug targets, understanding drug mechanism of action at the proteome (pharmacoproteomics) and metabolome level (pharmacometabolomics), and the potential to investigate drug toxicity and resistance will become possible

Celebrating the ‘Macromolecule’

It was in 1920 that Hermann Staudinger, the legendary German organic chemist, proposed the concept of ‘macromolecules’. Since then macromolecules have revolutionized the materials sciences and biosciences and supported the rapid growth of the plastics industry. It is not without surprise that the Rubber Technology Centre of IIT Kharagpur, which has spearheaded research in rubber and polymers since its inception in the 1980s, should think it fit to celebrate the beginning of the second century of the macromolecule with the holding of the International Conference on ‘Green and Sustainability in Polymers and Functional Materials: Opportunity and Challenges’, particularly at a time when the environmental alarm bells have been ringing loud.

The conference, held under the aegis of MHRD’s SPARC scheme and in collaboration with the University of Melbourne, saw three plenary lectures and 14 invited lectures by distinguished scientists, faculty members and technologists from the academia and industry, who talked about the recent advances in green polymerization techniques, the development of new and sustainable functional materials and the use of these in diverse applications that ranged from the automobile industry to drug delivery.

Of particular interest was the plenary lecture of Dr Muthupandian Ashokkumar of the School of Chemistry, University of Melbourne, who talked about the use of ultrasound in polymerization. It is known that the interaction of sound waves and gas bubbles in liquids lead to acoustic cavitation, and that the force of this interaction has been used to prepare food emulsions and extraction of useful compounds from plants and other materials. Dr Ashokkumar’s team is using the technique to ultrasonically encapsulate, in the core of chitosan-shelled microspheres, a non-polar liquid nutrient. The method could not only be used to deliver nutrients, such as milk, fruit juice etc., but it could also be used for the encapsulation and targeted delivery of drugs.

Dr. Sivaram, IISER PuneIn his inspiring plenary lecture, Dr S. Sivaram from IISER, Pune took the audience through the fractious yet scintillating history of the discovery of the ‘Macromolecule’ and showed how polymer science is indebted not merely to Staudinger, but to a host of other scientists, starting from Michael Faraday in 1826 – who first noticed ethylene and butene differed in their gas density, but had the same elemental composition, and opened up immense possibilities – to Wallace Carothers – who gave polymers its most acceptable definition – to Herman Mark in the late 20th century, who led the way for the X-ray crystallography of Macromolecules to show that a molecule could be larger than its unit cell.

Dr Nikos Hadjichristidis from King Abdullah University of Science and Technology, Saudi ArabiaDr Sivaram also talked about the future possibilities of aliphatic polyesters such as polylactic acid (PLLA) and its competitive advantage over PET as a biodegradable, sustainable option. “There is still scope for new monomers and improved chemistry to tailor the structure and properties of aliphatic polyesters as a platform for sustainable materials.” Prof. Vimal Katiyar from IIT Guwahati too talked about PLLA and explained how bionanofillers could vastly improve the properties of PLLA.

If Dr Sivaram made a case to return to monomers from polymers, in other words, take a relook at monomers, Dr Nikos Hadjichristidis from King Abdullah University of Science and Technology, Saudi Arabia, strengthened the case by talking about developing new thermoplastic elastomers from old monomers.

Prof. Kinsuk Naskar of IIT KharagpurNew techniques for the development of new functional materials were elaborated severally by the speakers. Among them were Dr Sayam Sen Gupta from IISER Kolkata, who talked about fabricating porous materials through self-assembly of inorganic nanoparticles and silk proteins, Prof. Kinsuk Naskar of IIT Kharagpur, who gave an overview of the generation of thermoplastic elastomers and thermoplastic vulcanizates, and Dr Nabendu B. Pramanik from the Department of Chemistry, Lehigh University, USA, who talked about the development of hyperthin polymeric membranes for the separation of carbondioxide from flue gas as a way to fight global warming. Dr Hirendra N. Ghosh from the Institute of Nano Science and Technology, Mohali, elucidated on a new technique regarding metal-semiconductor interface that could majorly impact the production of solar cell and optoelectronic devices.

Dr Virendra Kumar Gupta from Reliance IndustriesBoth the industry representatives – Dr Virendra Kumar Gupta from Reliance Industries, and Dr Sujit S. Nair from Ceat talked about their initiatives in developing high performance elastomers with self-healing properties or functionalized polymers for new generation green tires that will make up 90% of the need of the automobile industry in the near future. Both of them talked about their company’s collaboration with IIT Kharagpur in the development of these polymers. “We have collaborative projects with different industries like major petrochemical industries in India and abroad, different tire industries, different rubber and polymer manufacturing industries in India and abroad, coating, paint industries etc.” reminded Prof Santanu Chattopadhyay, Head of the Rubber Technology Centre.

A major emphasis of the conference was on the use of various polymers for drug delivery. Dr Suhrit Ghosh from the Indian Association for the Cultivation of Science talked about the use of biodegradable polydisulfide in efficient drug delivery and drug release. Dr Braja Gopal Bag of Vidyasagar University, Midnapore, talked about the use of hybrid material –terpenoids – extracted from plants which showed great promise in drug delivery. Prof. Santanu Dhara of IIT Kharagpur talked about the various advances made by the Biomaterials and Tissue Engineering group of the Institute in the development of customized biodegradable implants and the use of biological wastes for development of biopolymers and materials for healthcare delivery.

Dr Nabanita Saha of the University Institute, Tomas Bata University, Czech Republic gave the audience an introduction to her work in the development of magnetic insoles to help blood circulation in diabetic patients and the future prospects of ‘magnetic hydrogel’, a biomaterial that involved a polymer matrix. Prof. Rajat Das of IIT Kharagpur also talked about the development of highly stretchable, strong dual cross-linked self-healing hydrogels.

The conference also included poster and oral presentations by research scholars and masters students. Prof. Nikhil Singha, one of the coordinators of the conference said, “I am extremely happy to note that masters students and participants from Kolkata, Contai, Midnapore as well as countries across the world are attending the conference.”

New Repurposed Drugs & Methodology Identified by IIT Kharagpur Researchers

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Researchers from the School of Medical Science & Technology at IIT Kharagpur have identified new drug repurposing candidates for induction of fetal hemoglobin to treat beta-thalassemia patients

Blood disorders or hemoglobinopathies such as beta-thalassemia and sickle cell anemia affect millions. Drug-induced increase in fetal hemoglobin has been shown to improve the condition of those affected with these blood disorders. But these drugs have side-effects. Scientists are exploring if ‘repurposed’ or existing drugs can be used to treat these disorders. To find out which drugs could be used for possible repurposing the researchers at the Regenerative Medicine Lab at School of Medical Science and Technology of IIT Kharagpur studied the working of microRNAs which regulate the pathways along which the production of fetal hemoglobin is stimulated.

The researchers observed Curcumin, found in turmeric, and Ginsenoside, found in the roots of Ginseng, both known for their medicinal properties, could go a long way in treating blood disorders like thalassemia and sickle cell anemia. These two plant ingredients, together with approved drugs such as Valproate and Vorinostat were found to be ‘most suitable for future clinical trials’.

The researchers also studied how miRNAs work, how they regulate gene expressions and also which chemical molecules affect their expression pattern. The team at SMST used several bioinformatics tools to match differentially expressed miRNAs with differentially expressed genes (as found in publicly available datasets) and identify their pathways. The team has also devised a database called “miRwayDB” to provide comprehensive information of experimentally validated microRNA-pathway associations in various diseases. As many as 19 miRNAs were found to be differentially expressed in those who had high fetal hemoglobin levels in their blood. The team also identified some unique small molecules that strongly affected the expression of those 19 miRNAs.

Of the five molecules identified by the research, three – 5’-aza 2’-deoxycytidine, Valproate and Vorinostat – are commonly used to treat other diseases. For example, Valproate is used to treat seizure disorders in childhood and Vorinstat is an anticancer agent.

“These identified markers expand our understanding of fetal hemoglobin regulatory mechanism and may have importance in designing new therapeutic strategies to reactivate its production in patients with hemoglobin disorders,” said Prof. Nishant Chakravorty, who heads the Regenerative Medicine Lab and the team at SMST.

The study was conducted by Prof. Chakravorty, his student at SMST, Mr. Sankha Subhra Das, and Dr. Rashmi Sinha of IIT Kharagpur’s in-house medical facility B.C. Roy Technology Hospital and published in the “Gene” journal.

“Medical practitioners nowadays widely use repurposed drugs. An example is Sildenafil, which is used to treat impotence in males as well as neonatal pulmonary hypertension,” said Dr. Anish Chatterjee (MBBS, DCH, MD-Paediatrics), Professor, Dr. B C Roy Post Graduate Institute of Paediatric Sciences. Dr Chatterjee believes that research into repurposing of drugs is important and could even lower the cost of medical treatment as cheaper drugs, instead of costly ones presently used, could be used to treat diseases.

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Round India Winners

IIT Kharagpur Students among the Winners of India Finals of CFA Institute Research Challenge 2019-2020

A five-member student team from IIT Kharagpur has qualified for the Asia Pacific round of the CFA Institute Research Challenge 2019-2020. Along with IIM Ahmedabad and IIFT Delhi, the team from IIT Kharagpur have been won the India Finals of this Global level competition held on February 8, 2020. The Asia Pacific round is scheduled to be held on March 18-19 2020 in Seoul, South Korea. The AP Challenge will consist of one winner from each Member Society of the Asia Pacific Region, typically about 16-18 countries.

The final year students Shubham Maheshwari (Dual Degree, Metallurgical and Materials Engineering), Satwik Bansal (Dual Degree, Agricultural and Food Engineering), Daksh Thakkur (Dual Degree, Aerospace Engineering), Ritika Agarwal (Dual Degree, Agricultural and Food Engineering) and Tanay Jagani (Dual Degree, Agricultural and Food Engineering) who are all currently pursuing M.Tech. in Financial Engineering were mentored by Prof. Abhijeet Chandra from Vinod Gupta School of Management, the business school of IIT Kharagpur.

“A rigorous multi-disciplinary academic curriculum along with industry-ready skill-training has helped our students achieve this success at CFA Research Challenge India leg, along with other top b-schools of the country. IIT KGP’s team being only an undergraduate team has stood out in the competition mostly participated by MBA students. Financial Engineering, our unique interdisciplinary program run by the departments of Mathematics, Humanities & Social Sciences and Vinod Gupta School of Management, has always been appreciated by the industry. With our students competing with the best teams of Asia-Pacific region, we will mark our global footprints in financial research and valuation as well,” said Prof. Chandra.

The other finalists for India round included IIM Udaipur, IIM Calcutta, IIM Trichy, IIM Kozhikode, NMIMS. The teams qualified through the respective zonal rounds which witnessed participation from 59 leading business schools from across the country. The finalists presented their equity research on Reliance Nippon, HDFC Life, BATA and Oberoi Realty. The judges panel consisted of industry luminaries viz., Mr. Pankaj Tibrewal, Sr. Vice President & Equity Fund Manager, Kotak AMC, Mr. Varun Gupta, MD, Duff & Phelps (Asia Pacific Leader, Valuation Advisory Services and Country Leader, India) and Mr. Namit Arora, CFA, Managing Partner, IndGrowth Capital.

“It has been a thorough learning experience for us to participate in the CFA Institue Research Challenge. The competition has provided us with a platform to perform equity research under the able guidance of industry leaders of the investment management industry. We are looking forward to the Asia Pacific Regional round in Seoul, South Korea ,” opined partcipants Daksh Thakkur and Shubham Maheshwari.

The CFA Institute Research Challenge is an annual global competition that provides university students with hands-on mentoring and intensive training in financial analysis. Students work in teams to research and analyze a publicly-traded company — sometimes even meeting face-to-face with company management. Each team writes a research report on their assigned company with a buy, sell, or hold recommendation and may be asked to present and defend their analysis to a panel of industry professionals.

 

With content contributions from CFA Society India, CFA Institute Research Challenge in India

What’s Heating India?

Green-less Urbanization leading to India’s Heat Islands

Graphic: Suman Sutradhar

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An IIT Kharagpur study confirmed recently that the intensity of urban heat islands is positive in most cities (up to 2°C) in all seasons during day and night. The researchers from the Institute’s Centre for Oceans, Rivers, Atmosphere and Land Sciences (CORAL) and Department of Architecture and Regional Planning have found that most big cities of India with population more than one million, have positive heat island intensity during daytime while simultaneously showing an increasing trend in the nighttime urban heat island intensity. The study ‘Anthropogenic forcing exacerbating the urban heat islands in India‘ has been published in the international Elsevier publication Journal of Environmental Management (https://doi.org/10.1016/j.jenvman.2019.110006) .

The increase in global surface temperature or global warming is a great concern, especially the Urban Heat Island (UHI) phenomena which is among the major consequences of the alteration of the earth’s surface due to human activities. The relatively warmer temperatures in urban areas compared to their suburban areas has potential health hazards, such as mortality due to high temperatures and heatwaves, and pollution in urban areas, opine the researchers Sarath Raj, Prof. Saikat Kumar Paul, Prof. Arun Chakraborty and Prof. Jayanarayanan Kuttippurath.

The key finding in the study is the role of anthropogenic activities in increasing the urban temperature in India. As per a World Bank report, approximately a third of the total population in India (~7% of the total world population) lived in cities in 2018. The trend shows an increase of urbanization by almost 4% in the last decade, meaning people have moved away from rural areas to find work and make a living in the cities. To accommodate the additional needs of this increasing population the cities have witnessed some of the major human activities pertaining to changes in land use and land cover through a decrease in green cover, increase in impervious surface area and infrastructural development. In addition, the UHI situation demands more energy (e.g. fans and air-conditioners) that would trigger greenhouse gas emissions. These have led to modify the temperature of a city, remarks said lead author of the paper Sarath Raj.

“Our study is a detailed and careful analysis of urban heat islands of India which is the difference between urban and surrounding rural land surface temperatures, across all seasons in 44 major cities of India, for the period 2001-2017. For the first time we have found evidence of mean daytime Surface UHI Intensity (SUHII) going up to 2 °C for most cities, as analysed from satellite temperature measurements in monsoon and post-monsoon periods,” said Prof. Arun Chakraborty.

These data are also supported by the analysis of aerosols, night lights, precipitation and vegetation in the study regions. In areas like Kolkata, Pune, Guwahati etc where the urban areas are surrounded by large vegetated areas in suburban regions there is an enhanced cooling effect on surface in suburban areas during day as against cities like Delhi, Jaipur and cities in arid regions.

“Evidence from our study suggests that more green spaces within the city and its boundary could reduce the temperature in the city and its neighbourhood. Conservation and expansion of vegetated areas, and preserving water bodies in and around cities could be an effective strategy to curb the effects of urban heat islands. The construction of green buildings and selection of materials for buildings and other infrastructure such as eco-friendly materials could also prove to be crucial to mitigate the effects of heat islands,” said co-author Prof. Jayanarayanan Kuttippurath.

An earlier study published in Scientific Reports journal in 2017 had pointed out the correlation in UHI and the location of the smart cities proposed to be developed. In a global warming context, because the temperature is increasing across the latitudes, the background warming could add even more heat in the urban areas. Therefore, anthropogenic activities that augment the greenhouse gas emissions and atmospheric pollution should also be controlled to counter the adverse effects of urban heat islands. Keeping in mind India’s strong commitment towards the Climate Action, despite focus towards urbanization, such studies shall aid the planning and management of urban areas by giving insights about the effects of nature and intensity of development, land cover and land use mix and the structure of future smart city projects.